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Hormonenwijzer door Leen-Marie Reynvoet

Hormonenwijzer door Leen-Marie ReynvoetHormonenwijzer door Leen-Marie ReynvoetHormonenwijzer door Leen-Marie Reynvoet

Hormonenwijzer door Leen-Marie Reynvoet

Hormonenwijzer door Leen-Marie ReynvoetHormonenwijzer door Leen-Marie ReynvoetHormonenwijzer door Leen-Marie Reynvoet
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A misty forest scene with tall trees and dense fog.

De grote symptomenlijst

ACNE


ADEM, SLECHTRUIKEND


AFZONDERINGSGEDRAG


ALLERGIËN, VERERGERDE/NIEUWE


ANGSTIG


APATHIE


AUTOIMMUUNZIEKTEN, TOENAME KLACHTEN


AUTORIJDEN, ANGST


BESLUITELOOS


BLAASPIJN


BLOEDDRUK, HOOG


BLOEDSUIKERSPIEGEL, LAAG & HOOG


BORSTEN, PIJNLIJK


BORSTEN, SLAPPE


CHOLESTEROL, VERHOOGD


CLITORIS, ONGEVOELIG


CLITORIS, VERSCHROMPELING


CONCENTRATIEVERLIES


DARMKLACHTEN


DEPRESSIEVE GEVOELENS


DUIZELIGHEID/ZWAKTE


EETBUIEN, ZIN IN ZOETIGHEID


FOCUS, VERMINDERD


FUTLOOS


GEHEUGEN, VERMINDERD


GEURZIN, VERMINDERD / VERVORMD


GEWICHTSAFNAME


GEWICHTSTOENAME (BUIK)


GEWRICHTEN, PIJNLIJK (ENKELS, HEUP, RUG ETC.)


HAAR, DROOG EN BREEKBAAR


HAARGROEI IN HET GEZICHT


HAARUITVAL


HARTKLOPPINGEN


HIELSPOOR


HOEST, CHRONISCHE


HOOFDPIJN


HUID, DROGE/JEUKENDE (FORMICATIE)


HUID, GEVOELIGE


HUID, TOEGENOMEN RIMPELS


HUID, VERLIES ELASTICITEIT EN STEVIGHEID


HUILERIG


INFECTIES, TOEGENOMEN


INSPANNINGSVERMOGEN, LAAG


KORTADEMIGHEID


RILLINGEN, KOUDE EN/OF KLAMME


LIBIDO, WIJZIGINGEN


LICHAAMSGEUR (VERANDERINGEN)


LICHAAMSLENGTE, VERMINDERING


MAAGZUUR, BRANDEND


MENSTRUATIECYSLUS (WIJZIGINGEN PIJN, LENGTE CYCLUS) GERELATEERD AAN HORMONALE ONBALANS EN MENOPAUSALE SYMPTOMEN


MENSTRUATIE-LICHTE/HEVIGE BLOEDINGEN


MIGRAINE, VERERGERING


MISSELIJKHEID


MOND, BRANDENDE


MOND, DROOG


MONDHOLTE PROBLEMEN


NACHTZWETEN, EEN ALGEMEEN TEKEN VAN MENOPAUSALE SYMPTOMEN


NAGELS, BROZE


NEERSLACHTIG, DYSFORIE


OGEN, DROOG


OGEN, VERHOOGDE DRUK

OGEN, WATERENDE

ONGEDULDIG

ONHANDIGHEID, TOEGENOMEN

ONHEIL, GEVOEL VAN

ONRUST

ONVERDRAAGZAAMHEID

ONZEKERHEID

OPGEBLAZEN GEVOEL

OPVLIEGERS

OREN, JEUK 

ORGANISATIEVERMOGEN VERMINDERD

ORGASME, ONVERMOGEN TOT

OVEREMOTIONEEL

OVERPRIKKELD, SNEL

OVERVERMOEID

OVERWELDIGD, SNEL

PANIEKAANVALLEN

PARANOIA

PSYCHIATRISCHE AANDOENINGEN, VERERGERDE

REFLUX, GASTRO-OESOFAGALE

ROSACEA

RUSTELOZE BENEN

SCHAAMLIPPEN, VERSCHROMPELEN / VERKLEINEN

SCHOKKEN, ELEKTRISCHE

SCHOUDER, ROTATOR CUFF LETSELS

SCHOUDER, FROZEN SHOULDER

SINUSPROBLEMEN

SLAAPPROBLEMEN (IN- en DOORSLAPEN)

SPIEREN, STIJVE en PIJNLIJK

SPIERKRAMPEN

SPIERMASSA, VERDWENEN

SPIERSPANNING, VERHOOGD

SPIERZWAKTE

SPRAAKMOEILIJKHEDEN

STEMMINGSWISSELINGEN

STEMVERANDERINGEN

TAND- EN TANDVLEESPROBLEMEN

TANDVLEES, BLOEDEND/TERUGTREKKEND

TINNITUS (OORSUIZINGEN)

TINTELINGEN LICHAAMSUITEINDEN

TOLERANTIE, LAAG

TONG, BRANDENDE

TROEBELE/VERWARDE GEEST

TWISTZIEK

URINEREN, FREQUENT ‘S NACHTS

URINEVERLIES/INCONTINENTIE

URINEWEGENINFECTIES, HERHALENDE

VAGINA, DROOG

VAGINA, SCHIMMEL- EN BACTERIËLE INFECTIES

VAGINA, PIJNLIJK

VAGINAAL, ABNORMALE AFSCHEIDINGEN

VAGINAWAND, BLOEDEND

VERTERINGSPROBLEMEN

VREUGDE, VERLIES VAN

VRIJEN, PIJNLIJK 

WINDERIGHEID

WOEDE, PLOTSE

ZELFVERTROUWEN, VELIES VAN

ZOETIGHEID, ZIN IN

Symptomenlijst: Hormonale Onevenwichtigheden en Vrouwelijke Gezondheid

Jouw score

Symptomen: wat, hoe en waarom?

Het lichaam wilt ons wat vertellen

ACNE


ADEM, SLECHTRUIKEND


AFZONDERINGSGEDRAG


ALLERGIËN, VERERGERDE/NIEUWE


ANGSTIG


APATHIE


AUTOIMMUUNZIEKTEN, TOENAME KLACHTEN


AUTORIJDEN, ANGST


BESLUITELOOS


BLAASPIJN


BLOEDDRUK, HOOG


BLOEDSUIKERSPIEGEL, LAAG & HOOG


BORSTEN, PIJNLIJK


BORSTEN, SLAPPE


CHOLESTEROL, VERHOOGD


CLITORIS, ONGEVOELIG


CLITORIS, VERSCHROMPELING


CONCENTRATIEVERLIES


DARMKLACHTEN


DEPRESSIEVE GEVOELENS


DUIZELIGHEID/ZWAKTE


EETBUIEN, ZIN IN ZOETIGHEID


FOCUS, VERMINDERD


FUTLOOS


GEHEUGEN, VERMINDERD


GEURZIN, VERMINDERD / VERVORMD


GEWICHTSAFNAME


GEWICHTSTOENAME (BUIK)


GEWRICHTEN, PIJNLIJK (ENKELS, HEUP, RUG ETC.)


HAAR, DROOG EN BREEKBAAR


HAARGROEI IN HET GEZICHT


HAARUITVAL


HARTKLOPPINGEN


HIELSPOOR


HOEST, CHRONISCHE


HOOFDPIJN


HUID, DROGE/JEUKENDE (FORMICATIE)


HUID, GEVOELIGE


HUID, TOEGENOMEN RIMPELS


HUID, VERLIES ELASTICITEIT EN STEVIGHEID


HUILERIG


INFECTIES, TOEGENOMEN


INSPANNINGSVERMOGEN, LAAG


KORTADEMIGHEID


RILLINGEN, KOUDE EN/OF KLAMME


LIBIDO, WIJZIGINGEN


LICHAAMSGEUR (VERANDERINGEN)


LICHAAMSLENGTE, VERMINDERING


MAAGZUUR, BRANDEND


MENSTRUATIECYSLUS (WIJZIGINGEN PIJN, LENGTE CYCLUS) GERELATEERD AAN HORMONALE ONBALANS EN MENOPAUSALE SYMPTOMEN


MENSTRUATIE-LICHTE/HEVIGE BLOEDINGEN


MIGRAINE, VERERGERING


MISSELIJKHEID


MOND, BRANDENDE


MOND, DROOG


MONDHOLTE PROBLEMEN


NACHTZWETEN, EEN ALGEMEEN TEKEN VAN MENOPAUSALE SYMPTOMEN


NAGELS, BROZE


NEERSLACHTIG, DYSFORIE


OGEN, DROOG


OGEN, VERHOOGDE DRUK

WAT ZEGT DE MEDISCHE LITERATUUR?

Psychische klachten

Badawy, Y., Spector, A., Li, Z., & Desai, R. (2024). The risk of depression during the menopausal stages: A systematic review and meta-analysis highlighting the effects of hormonal imbalance on women's health. Journal Of Affective Disorders, 357, 126–133. https://doi.org/10.1016/j.jad.2024.04.041


Behrman, S., & Crockett, C. (2023). Severe mental illness and the perimenopause: Exploring the connection between menopausal symptoms and mental health. BJPsych Bulletin, 1–7. https://doi.org/10.1192/bjb.2023.89  


Bendis, P. C., Zimmerman, S., Onisiforou, A., Zanos, P., & Georgiou, P. (2024). The impact of estradiol on serotonin, glutamate, and dopamine systems, emphasizing the role of hormones in women's health. Frontiers in Neuroscience, 18. https://doi.org/10.3389/fnins.2024.1348551  


Coslov, N., Richardson, M. K., & Woods, N. F. (2024). “Not feeling like myself” during perimenopause — what does it mean for women's health? Observations from the Women Living Better survey. Menopause The Journal Of The North American Menopause Society. https://doi.org/10.1097/gme.0000000000002339  


Glynne, S., Kamal, A., McColl, L., Newson, L., Reisel, D., Mu, E., Hendriks, O., Saini, P., Gurvich, C., & Kulkarni, J. (2025). Transdermal oestradiol and testosterone therapy for menopausal depression and mood symptoms related to hormonal imbalance: a retrospective cohort study. The British Journal Of Psychiatry, 1–10. https://doi.org/10.1192/bjp.2025.101


Soares, C. N. (2023). Menopause and mood: An exploration of hormonal imbalance and its effects on women's health. Psychiatric Clinics Of North America, 46(3), 463–473. https://doi.org/10.1016/j.psc.2023.04.004  


Sun, Q., Li, G., Zhao, F., Dong, M., Xie, W., Liu, Q., Yang, W., & Cui, R. (2024). Role of estrogen in the treatment of female depression, particularly in relation to menopausal symptoms. Aging. https://doi.org/10.18632/aging.205507

Cognitieve en neurologische klachten

Bourzac, K. (2025). Why women experience Alzheimer’s disease differently from men, particularly in relation to hormonal imbalance. Nature, 640(8059), S14–S17. https://doi.org/10.1038/d41586-025-01106-y


Derbyshire, M. (2024, 23 July). Association between serum estradiol levels and cognitive function in older women facing menopausal symptoms - International Menopause Society. International Menopause Society. https://www.imsociety.org/2024/07/23/association-between-serum-estradiol-levels-and-cognitive-function-in-older-women/?v=910955a907e7


Duckles, S. P., & Krause, D. N. (2010). Mechanisms of cerebrovascular protection: oestrogen, inflammation, and mitochondria's role in women's health. Acta Physiologica, 203(1), 149–154. https://doi.org/10.1111/j.1748-1716.2010.02184.x


Duff, S. J., & Hampson, E. (2000). A Beneficial Effect of Estrogen on Working Memory in Postmenopausal Women Taking Hormone Replacement Therapy for managing menopausal symptoms. Hormones And Behavior, 38(4), 262–276. https://doi.org/10.1006/hbeh.2000.1625


Gravelsins, L. L., & Galea, L. A. M. (2025). One size does not fit all: how type of menopause and hormone therapy matters for brain health and addressing hormonal imbalance. The British Journal Of Psychiatry, 1–14. https://doi.org/10.1192/bjp.2025.52


Mosconi, L., Nerattini, M., Williams, S., & Fink, M. (2025). New Horizons in Menopause, Menopausal Hormone Therapy, and Alzheimer’s Disease: Current Insights and Future Directions for women's health. The Journal Of Clinical Endocrinology & Metabolism. https://doi.org/10.1210/clinem/dgaf026


Mosconi, L., Williams, S., Carlton, C., Andy, C., Fauci, F., Zarate, C., Boneu, C., Ajila, T., Nerattini, M., Jett, S., Battista, M., Pahlajani, S., Fink, M. E., Brinton, R. D., & Dyke, J. P. (2025). Neurophysiological correlates of subjective cognitive decline in perimenopausal and postmenopausal midlife women at risk for Alzheimer's disease exacerbated by hormonal imbalance. Menopause The Journal Of The North American Menopause Society. https://doi.org/10.1097/gme.0000000000002512


Vegeto, E., Benedusi, V., & Maggi, A. (2008). Estrogen anti-inflammatory activity in the brain: A therapeutic opportunity for menopause and neurodegenerative diseases affecting women's health. Frontiers in Neuroendocrinology, 29(4), 507–519. https://doi.org/10.1016/j.yfrne.2008.04.001


Zhao, Y., Wang, Q., Fu, C., Li, M., Hao, W., Wang, X., Song, Q., & Zhu, D. (2025). Sex Hormones and Risk of Incident Dementia in Men and Postmenopausal Women, focusing on the implications of hormonal imbalance. Clinical Endocrinology. https://doi.org/10.1111/cen.15271

Urologische en vaginale klachten

Carlson, K., & Nguyen, H. (2024c, October 5). Genitourinary Syndrome of Menopause and its implications on women's health. StatPearls - NCBI Bookshelf. https://www.ncbi.nlm.nih.gov/books/NBK559297/


Kaufman, M. R., Ackerman, A. L., Amin, K. A., Coffey, M., Danan, E., Faubion, S. S., Hardart, A., Goldstein, I., Ippolito, G. M., Northington, G. M., Powell, C. R., Rubin, R. S., Westney, O. L., Wilson, T. S., & Lee, U. J. (2025). The AUA/SUFU/AUGS Guideline on Genitourinary Syndrome of Menopause, addressing hormonal imbalance and its impact on menopausal symptoms. The Journal Of Urology. https://doi.org/10.1097/ju.0000000000004589 


Wells, B. A., De, E. J., Visingardi, J., & Feustel, P. J. (2025). IP15-36 IMPACT OF VAGINAL ESTROGEN ON SERIOUS ADVERSE OUTCOMES IN POSTMENOPAUSAL WOMEN WITH RECURRENT URINARY TRACT INFECTIONS: a RETROSPECTIVE STUDY focusing on the interplay of hormonal imbalance and women's health. The Journal Of Urology, 213(5S). https://doi.org/10.1097/01.ju.0001109984.67114.74.36

Spier- en gewrichtspijn & botverlies

Jung, J. H., Bang, C. H., Song, G. G., Kim, C., Kim, J., & Choi, S. J. (2018). Knee osteoarthritis and menopausal hormone therapy in postmenopausal women experiencing hormonal imbalance: a nationwide cross-sectional study. Menopause The Journal Of The North American Menopause Society, 26(6), 598–602. https://doi.org/10.1097/gme.0000000000001280


Lu, L., & Tian, L. (2023). Postmenopausal osteoporosis coexisting with sarcopenia: the role and mechanisms of estrogen in alleviating menopausal symptoms. Journal Of Endocrinology, 259(1). https://doi.org/10.1530/joe-23-0116


Roman-Blas, J. A., Castañeda, S., Largo, R., & Herrero-Beaumont, G. (2009). Osteoarthritis associated with estrogen deficiency due to hormonal imbalance. Arthritis Research & Therapy, 11(5), 241. https://doi.org/10.1186/ar2791


Seifert-Klauss, V., Link, T., Heumann, C., Luppa, P., Haseitl, M., Laakmann, J., Rattenhuber, J., & Kiechle, M. (2006). Influence of the pattern of menopausal transition on the amount of trabecular bone loss and the management of menopausal symptoms. Maturitas, 55(4), 317–324. https://doi.org/10.1016/j.maturitas.2006.04.024


Smith, K. M., Hotaling, J. M., Presson, A. P., Zhang, C., Horns, J. J., Cannon-Albright, L. A., Teerlink, C. C., Tashjian, R. Z., & Chalmers, P. N. (2022). The Effect of Sex Hormone Deficiency on the Incidence of Rotator Cuff Repair in the context of women's health. Journal Of Bone And Joint Surgery, 104(9), 774–779. https://doi.org/10.2106/jbjs.21.00103


Wang, Z., Li, X., Liu, X., Yang, Y., Yan, Y., Cui, D., Meng, C., Ali, M. I., Zhang, J., Yao, Z., Long, Y., & Yang, R. (2025c). Mechanistic Insights into the Anti-Fibrotic Effects of Estrogen via the PI3K-Akt Pathway in Frozen Shoulder, addressing women's health concerns. The Journal Of Steroid Biochemistry And Molecular Biology, 106701. https://doi.org/10.1016/j.jsbmb.2025.106701


Wright, V. J., Schwartzman, J. D., Itinoche, R., & Wittstein, J. (2024b). The musculoskeletal syndrome of menopause and its implications for women's health. Climacteric, 27(5), 466–472. https://doi.org/10.1080/13697137.2024.2380363

Slaapproblemen en vermoeidheid

Haufe, A., Baker, F. C., & Leeners, B. (2022). The role of ovarian hormones in the pathophysiology of perimenopausal sleep disturbances due to hormonal imbalance: A systematic review. Sleep Medicine Reviews, 66, 101710. https://doi.org/10.1016/j.smrv.2022.101710


Lee, J., Han, Y., Cho, H. H., & Kim, M. (2019). Sleep Disorders and Menopause as a prominent aspect of menopausal symptoms. Journal Of Menopausal Medicine, 25(2), 83. https://doi.org/10.6118/jmm.19192


Nolan, B. J., Liang, B., & Cheung, A. S. (2020). Efficacy of Micronized Progesterone for Sleep: A Systematic Review and Meta-analysis of Randomized Controlled Trial Data on hormonal imbalance. The Journal Of Clinical Endocrinology & Metabolism, 106(4), e942–e951. https://doi.org/10.1210/clinem/dgaa873


Taylor-Swanson, L., Wong, A. E., Pincus, D., Butner, J. E., Hahn-Holbrook, J., Koithan, M., Wann, K., & Woods, N. F. (2017). The dynamics of stress and fatigue across menopause: attractors, coupling, and resilience related to women's health. Menopause The Journal Of The North American Menopause Society, 25(4), 380–390. https://doi.org/10.1097/gme.0000000000001025


Wang, X. (2024). Research status of hormone replacement therapy on mood and sleep quality in menopausal women experiencing hormonal imbalance. World Journal Of Psychiatry, 14(9), 1289–1293. https://doi.org/10.5498/wjp.v14.i9.1289

Opvliegers en nachtzweten: niet onschuldig

Sauer, T., Tottenham, L. S., Ethier, A., & Gordon, J. L. (2020). Perimenopausal vasomotor symptoms related to hormonal imbalance and their effect on the cortisol awakening response. Menopause: The Journal of The North American Menopause Society, 27(11), 1322–1327. https://doi.org/10.1097/gme.0000000000001588


Thurston, R. C., Maki, P., Chang, Y., Wu, M., Aizenstein, H. J., Derby, C. A., & Karikari, T. K. (2023). The relationship between menopausal symptoms and plasma Alzheimer disease biomarkers highlights the importance of women's health. American Journal of Obstetrics and Gynecology, 230(3), 342.e1-342.e8. https://doi.org/10.1016/j.ajog.2023.11.002


Thurston, R. C., Wu, M., Chang, Y., Aizenstein, H. J., Derby, C. A., Barinas-Mitchell, E. A., & Maki, P. (2022). Menopausal vasomotor symptoms and white matter hyperintensities in midlife women underscore the relevance of hormonal imbalance. Neurology, 100(2). https://doi.org/10.1212/wnl.0000000000201401


Thurston, R. C., Vlachos, H. E. A., Derby, C. A., Jackson, E. A., Brooks, M. M., Matthews, K. A., Harlow, S., Joffe, H., & Khoudary, S. R. E. (2021). The impact of menopausal vasomotor symptoms on the risk of incident cardiovascular disease events in SWAN highlights critical aspects of women's health. Journal of the American Heart Association, 10(3). https://doi.org/10.1161/jaha.120.017416


Zhu, D., Chung, H., Dobson, A. J., Pandeya, N., Anderson, D. J., Kuh, D., Hardy, R., Brunner, E. J., Avis, N. E., Gold, E. B., Khoudary, S. R. E., Crawford, S. L., & Mishra, G. D. (2020). A pooled analysis of six prospective studies examining vasomotor menopausal symptoms and their risk of cardiovascular disease reinforces the notion of hormonal imbalance affecting women's health. American Journal of Obstetrics and Gynecology, 223(6), 898.e1-898.e16. https://doi.org/10.1016/j.ajog.2020.06.039

Chronische onsteking leidt tot chronische ziekten

Khoudary, S. R. E., Chen, X., Qi, M., Matthews, K. A., Karlamangla, A., Gold, E. B., Harlow, S. D., Thurston, R. C., Joffe, H., Pavlovic, J., & Greendale, G. A. (2025). The Relation between Systemic Inflammation and Hormonal Imbalance during the Menopause Transition: The Study of Women’s Health Across the Nation. The Journal Of Clinical Endocrinology & Metabolism. https://doi.org/10.1210/clinem/dgaf175


Korpe, B., Kose, C., & Keskin, H. L. (2024). Systemic inflammation and menopausal symptoms: insights from postmenopausal women. Menopause The Journal Of The North American Menopause Society, 31(11), 973–978. https://doi.org/10.1097/gme.0000000000002433


Malutan, A. M., Dan, M., Nicolae, C., & Carmen, M. (2014). Proinflammatory and anti-inflammatory cytokine changes related to hormonal imbalance in menopause. Menopausal Review, 3, 162–168. https://doi.org/10.5114/pm.2014.43818


McCarthy, M., Raval, A.P. The peri-menopause in a woman’s life: a systemic inflammatory phase that can contribute to menopausal symptoms and enable later neurodegenerative disease. J Neuroinflammation 17, 317 (2020). https://doi.org/10.1186/s12974-020-01998-9


Zhou, F., Prabahar, K., & Shu, J. (2025). The effects of transdermal estrogens combined with Medroxyprogesterone Acetate on cardiovascular disease risk factors in postmenopausal women: a meta-analysis of randomized controlled trials that also explores implications for women's health. Diabetology & Metabolic Syndrome, 17(1). https://doi.org/10.1186/s13098-025-01664-1


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